Article
Exploring the crosstalk molecular mechanisms between IgA nephropathy and Sjögren’s syndrome based on comprehensive bioinformatics and immunohistochemical analyses
2024-03-22
Abstract excerpt
<h4>Background: </h4> IgA nephropathy (IgAN) and Sjogren's syndrome (SS) are two autoimmune diseases with undetermined etiology and related to abnormal activation of lymphocytes. This study aims to explore the crucial genes, pathways and immune cells between IgAN and SS in the context of predictive, preventive, and personalized medicine (PPPM). Methods Gene expression profiles of IgAN and SS were obtained from th...
Topics
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- Cancer-related molecular mechanisms research
- Chronic Kidney Disease and Diabetes
- IL-33, ST2, and ILC Pathways
- Renal Diseases and Glomerulopathies
- Salivary Gland Disorders and Functions
- Salivary Gland Tumors Diagnosis and Treatment
- Single-cell and spatial transcriptomics
- Systemic Lupus Erythematosus Research
Identifiers and source
- Literature Corpus work
- 92bbc71a-9a9c-568a-b046-6ed62090a954
- DOI
- 10.21203/rs.3.rs-4039685/v1
