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Identification of key necroptosis-related genes and immune landscape in patients with immunoglobulin A nephropathy

18 Dec 2024

Abstract excerpt

BACKGROUND: Immunoglobulin A nephropathy (IgAN) is a major cause of chronic kidney disease (CKD) and kidney failure. Necroptosis is a novel type of programmed cell death that has been proved to be associated with the pathogenesis of infectious disease, cardiovascular disease, neurological disorders and so on. However, the role of necroptosis in IgAN remains unclear. METHODS: In this study, we explored the role of...

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PMID: 39696012
DOI: 10.1186/s12882-024-03885-4

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