Article

Molecular and clinicopathological characteristics of EGFR gene fusions in 35,023 Chinese patients with solid tumors

2023-06-22

Abstract excerpt

Epidermal growth factor receptor ( EGFR) fusions are rare but potentially actionable oncogenic drivers across multiple solid tumors. Here, we assessed the incidence of EGFR fusions and described their impact on prognosis in solid tumors. Panel-based next-generation sequencing (NGS) data of 35,023 patients with different types of solid tumors were collected and analyzed from the Simcere Diagnostics (Nanjing, China)...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: b88a9b65-688d-56ea-9a9e-6cb0f9ec58ab
DOI: 10.21203/rs.3.rs-3061345/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Molecular and clinicopathological characteristics of EGFR gene fusions in 35,023 Chinese patients with solid tumorsDOI 10.21203/rs.3.rs-3061345/v1Read

Distribution of EGFR fusions in 35,023 Chinese patients with solid tumors-the frequency, fusion partners and clinical outcome.Semantic proximity Read

Distribution of EGFR fusions in 35,023 Chinese patients with solid tumors-the frequency, fusion partners and clinical outcomeSemantic proximity Read

Oncogenic gene fusions in cancer: from biology to therapySemantic proximity Read

Detection of NRG1 Gene Fusions in Solid TumorsSemantic proximity Read

Identification of RET fusions in a Chinese multicancer retrospective analysis by next‐generation sequencingSemantic proximity Read

Prevalence and clinico-genomic characteristics of patients with TRK fusion cancer in ChinaSemantic proximity Read

Molecular characterization of MET fusions from a large real-world Chinese population: A multicenter study.Semantic proximity Read

Fusion genes in gynecologic tumors: the occurrence, molecular mechanism and prospect for therapySemantic proximity Read

Genomic characterization and outcome evaluation of kinome fusions in lung cancer revealed novel druggable fusionsSemantic proximity Read

Characterizing the molecular and clinical implications of NRG1 fusions in NSCLC through integrated RNA and DNA sequencing analysis.Semantic proximity Read

Landscape of potentially targetable receptor tyrosine kinase fusions in diverse cancers by DNA-based profilingSemantic proximity Read

Clinically relevant fusion oncogenes: detection and practical implicationsSemantic proximity Read