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Identification and verification of the optimal feature genes of ferroptosis in thyroid-associated orbitopathy

13 Dec 2024

Abstract excerpt

Background Thyroid-associated orbitopathy (TAO) is an autoimmune inflammatory disorder of the orbital adipose tissue, primarily causing oxidative stress injury and tissue remodeling in the orbital connective tissue. Ferroptosis is a form of programmed cell death driven by the accumulation of reactive oxygen species (ROS), iron metabolism disorder, and lipid peroxidation. This study aims to identify and validate...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 39735537
DOI: 10.3389/fimmu.2024.1422497

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