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The role of Sirtuin 1 and its activators in age-related lung disease

3 Apr 2023

Abstract excerpt

-dependent deacetylase that regulates inflammation and stress resistance. SIRT1 acts by inducing the deacetylation of various substrates and regulates several mechanisms that relate to lung aging, such as genomic instability, lung stem cell exhaustion, mitochondrial dysfunction, telomere shortening, and immune senescence. Chinese herbal medicines have many biological activities, exerting anti-inflammatory,...

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PMID: 37018986
DOI: 10.1016/j.biopha.2023.114573

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