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Article

Caveolin-1 genotypes as predictor for locoregional recurrence and contralateral disease in breast cancer.

Breast cancer research and treatment - 1 Jun 2023

Godina Christopher, Tryggvadottir Helga, Bosch Ana, Borgquist Signe, Belting Mattias, Isaksson Karolin, Jernström Helena

Abstract excerpt

PURPOSE: Caveolin-1 (CAV1) has been implicated in breast cancer oncogenesis and metastasis and may be a potential prognosticator, especially for non-distant events. CAV1 functions as a master regulator of membrane transport and cell signaling. Several CAV1 SNPs have been linked to multiple cancers, but the prognostic impact of CAV1 SNPs in breast cancer remains unclear. Here, we investigated CAV1 polymorphisms in...

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Identifiers

PMID: 37017811
DOI: 10.1007/s10549-023-06919-x
PMCID: PMC10175335

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