Article
OCA2 rs4778137 polymorphism predicts survival of breast cancer patients receiving neoadjuvant chemotherapy.
Gene - 20 Apr 2018
Li Xiao-Ping, Lan Jian-Yun, Liu Dong-Qin, Zhou Hang, Qian Miao-Miao, Wang Wei-Wei, Yang Man
Abstract excerpt
BACKGROUND: Genome-wide association study (GWAS) studies have showed that single nucleotide polymorphisms (SNPs) in OCA2 gene were associated with the survival of breast cancer patients treated with adjuvant chemotherapy. To further explain the association between OCA2 SNPs and breast cancer survival, we investigated the predictive value of rs4778137 located in OCA2 in local advanced breast cancer patients...
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