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Article

Discovery of actionable genetic alterations with targeted panel sequencing in children with relapsed or refractory solid tumors.

PloS one - 1 Jan 2019

Lee Ji Won, Kim Nayoung K D, Lee Soo Hyun, Cho Hee Won, Ma Youngeun, Ju Hee Young, Yoo Keon Hee, Sung Ki Woong, Koo Hong Hoe, Park Woong-Yang

Abstract excerpt

Advances in genomic technologies and the development of targeted therapeutics are making the use of precision medicine increasingly possible. In this study, we explored whether precision medicine can be applied for the management of refractory/relapsed pediatric solid tumors by discovering actionable alterations using targeted panel sequencing. Samples of refractory/relapsed pediatric solid tumors were tested...

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Identifiers

PMID: 31747416
DOI: 10.1371/journal.pone.0224227
PMCID: PMC6867621

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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