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Article

Novel polymorphisms in caspase-8 are associated with breast cancer risk in the California Teachers Study.

BMC cancer - 12 Jan 2016

Park Hannah Lui, Ziogas Argyrios, Chang Jenny, Desai Bhumi, Bessonova Leona, Garner Chad, Lee Eunjung, Neuhausen Susan L, Wang Sophia S, Ma Huiyan, Clague Jessica, Reynolds Peggy, Lacey James V, Bernstein Leslie, Anton-Culver Hoda

Abstract excerpt

BACKGROUND: The ability of tamoxifen and raloxifene to decrease breast cancer risk varies among different breast cancer subtypes. It is important to determine one's subtype-specific breast cancer risk when considering chemoprevention. A number of single nucleotide polymorphisms (SNPs), including one in caspase-8 (CASP8), have been previously associated with risk of developing breast cancer. Because caspase-8 is...

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Identifiers

PMID: 26758508
DOI: 10.1186/s12885-015-2036-9
PMCID: PMC4711015

Genes

CASP8

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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