Article
Investigation of Dombrock Blood Group Alleles and Genotypes among Saudi Blood Donors in Southwestern Saudi Arabia.
Genes - 17 Jun 2022
Halawani Amr J, Mansor Abdullah S, Assaggaf Hamza M, Almasmoum Hibah A, Abu-Tawil Hisham I, Alsharif Khalaf F, Dobie Gasim, Habibullah Mahmoud M
Abstract excerpt
The Dombrock (DO) blood group system has two primary antigens, Doa and Dob, which can cause delayed hemolytic transfusion reactions. The paucity of specific monospecific antibodies can hamper the typing based on these antigens. Thus, blood group genotyping (BGG) was investigated as a possible solution. Sequence-specific primers were designed to target a single nucleotide polymorphism (rs11276) on the ART4 gene...
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