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Accurately Detection of A-Globin Gene Copy Number Variants With Two Reactions Using Droplet Digital PCR

2021-08-06

Abstract excerpt

<title>Abstract</title> <p><bold>Background: </bold>α-thalassemia, with carrier rates of 11.31% and 17.55% respectively in Guangdong and Guangxi province, is a highly prevalent disease in Southern China and tropical and subtropical regions and is mainly caused by deletion in α-globin gene (<italic>HBA1</italic> and <italic>HBA2</italic>). The clinical manifestation of α-thalassemia is highly correlated with the c...

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Literature Corpus work: d9e2dae1-6fe8-59bb-8cc5-e32cf8fb11f1
DOI: 10.21203/rs.3.rs-765129/v1

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