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Detection of blood group genes using multiplex SNaPshot method.

Transfusion - 1 Apr 2009

Palacajornsuk Poonsub, Halter Christine, Isakova Victoria, Tarnawski Michal, Farmar James, Reid Marion E, Chaudhuri Asok

Abstract excerpt

BACKGROUND: The determination of blood group antigens in patients and donors is of primary importance in transfusion medicine. Blood group antigens are inherited and are polymorphic in nature. The majority of polymorphic blood group antigens arise from single-nucleotide polymorphisms (SNPs) in the blood group genes. Many DNA-based assays, such as species-specific polymerase chain reaction (PCR), PCR-restriction...

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PMID: 19170993
DOI: 10.1111/j.1537-2995.2008.02053.x

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