Article
A dopamine receptor D2 genetic polymorphism associated with transition to mental disorders in a cohort of individuals with at-risk mental state for psychosis.
Revista brasileira de psiquiatria (Sao Paulo, Brazil : 1999) - 1 Jan 2000
Marques Julia Hatagami, Talib Leda Leme, Hortêncio Lucas, Andrade Julio Cesar, Alves Tania Maria, Serpa Mauricio Henriques, Yamamoto Guilherme Lopes, van de Bilt Martinus Theodorus, Rössler Wulf, Gattaz Wagner Farid, Loch Alexandre Andrade
Abstract excerpt
OBJECTIVES: To test the association of 45 single nucleotide polymorphisms (SNPs) with transition to psychiatric disorders in a cohort of individuals at ultrahigh risk (UHR) mental state for psychosis. METHODS: Through general population screening, 88 non-help-seeking UHR subjects and 130 healthy control individuals were genotyped for 45 SNPs related to psychosis. They were followed for a mean of 2.5 years, and...
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