Article
Effects of NRG1 and DAOA genetic variation on transition to psychosis in individuals at ultra-high risk for psychosis.
Translational psychiatry - 30 Apr 2013
Bousman C A, Yung A R, Pantelis C, Ellis J A, Chavez R A, Nelson B, Lin A, Wood S J, Amminger G P, Velakoulis D, McGorry P D, Everall I P, Foley D L
Abstract excerpt
Prospective studies have suggested genetic variation in the neuregulin 1 (NRG1) and D-amino-acid oxidase activator (DAOA) genes may assist in differentiating high-risk individuals who will or will not transition to psychosis. In a prospective cohort (follow-up=2.4-14.9 years) of 225 individuals at ultra-high risk (UHR) for psychosis, we assessed haplotype-tagging single-nucleotide polymorphisms (htSNPs) spanning...
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