Article
Methylomic changes during conversion to psychosis.
Molecular psychiatry - 1 Apr 2017
Kebir O, Chaumette B, Rivollier F, Miozzo F, Lemieux Perreault L P, Barhdadi A, Provost S, Plaze M, Bourgin J, Gaillard R, Mezger V, Dubé M-P, Krebs M-O
Abstract excerpt
The onset of psychosis is the consequence of complex interactions between genetic vulnerability to psychosis and response to environmental and/or maturational changes. Epigenetics is hypothesized to mediate the interplay between genes and environment leading to the onset of psychosis. We believe we performed the first longitudinal prospective study of genomic DNA methylation during psychotic transition in...
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