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Article

Genetic association of lipids and lipid-lowering drug target genes with non-alcoholic fatty liver disease.

EBioMedicine - 1 Apr 2023

Li Ziang, Zhang Bin, Liu Qingrong, Tao Zhihang, Ding Lu, Guo Bo, Zhang Erli, Zhang Haitong, Meng Zhen, Guo Shuai, Chen Yang, Peng Jia, Li Jinyue, Wang Can, Huang Yingbo, Xu Haiyan, Wu Yongjian

Abstract excerpt

BACKGROUND: Some observational studies found that dyslipidaemia is a risk factor for non-alcoholic fatty liver disease (NAFLD), and lipid-lowering drugs may lower NAFLD risk. However, it remains unclear whether dyslipidaemia is causative for NAFLD. This Mendelian randomisation (MR) study aimed to explore the causal role of lipid traits in NAFLD and evaluate the potential effect of lipid-lowering drug targets on...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 37002989
DOI: 10.1016/j.ebiom.2023.104543
PMCID: PMC10070091

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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