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Genetic Pathways in Nonalcoholic Fatty Liver Disease: Insights From Systems Biology

14 Mar 2020

Abstract excerpt

Nonalcoholic fatty liver disease (NAFLD) represents a burgeoning worldwide epidemic whose etiology reflects multiple interactions between environmental and genetic factors. Here, we review the major pathways and dominant genetic modifiers known to be relevant players in human NAFLD and which may determine key components of the heritability of distinctive disease traits including steatosis and fibrosis. In...

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PMID: 32170962
DOI: 10.1002/hep.31229

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