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Article

Within-host genetic diversity of SARS-CoV-2 lineages in unvaccinated and vaccinated individuals.

Nature communications - 31 Mar 2023

Gu Haogao, Quadeer Ahmed Abdul, Krishnan Pavithra, Ng Daisy Y M, Chang Lydia D J, Liu Gigi Y Z, Cheng Samuel M S, Lam Tommy T Y, Peiris Malik, McKay Matthew R, Poon Leo L M

Abstract excerpt

Viral and host factors can shape SARS-CoV-2 evolution. However, little is known about lineage-specific and vaccination-specific mutations that occur within individuals. Here, we analysed deep sequencing data from 2,820 SARS-CoV-2 respiratory samples with different viral lineages to describe the patterns of within-host diversity under different conditions, including vaccine-breakthrough infections. In unvaccinated...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 37002233
DOI: 10.1038/s41467-023-37468-y
PMCID: PMC10063955

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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