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Article

Vaccination Shapes Within-Host SARS-CoV-2 Diversity of Omicron BA.2.2 Breakthrough Infection.

The Journal of infectious diseases - 14 Jun 2024

Zhang Yi, Zhou Yang, Chen Jiazhen, Wu Jing, Wang Xun, Zhang Yumeng, Wang Shiyong, Cui Peng, Xu Yuanyuan, Li Yang, Shen Zhongliang, Xu Tao, Zhang Qiran, Cai Jianpeng, Zhang Haocheng, Wang Pengfei, Ai Jingwen, Jiang Ning, Qiu Chao, Zhang Wenhong

Abstract excerpt

BACKGROUND: Low-frequency intrahost single-nucleotide variants of SARS-CoV-2 have been recognized as predictive indicators of selection. However, the impact of vaccination on the intrahost evolution of SARS-CoV-2 remains uncertain at present. METHODS: We investigated the genetic variation of SARS-CoV-2 in individuals who were unvaccinated, partially vaccinated, or fully vaccinated during Shanghai's Omicron BA.2.2...

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PMID: 38149984
DOI: 10.1093/infdis/jiad572

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