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Cell atlas of CCl4-induced progressive liver fibrosis reveals stage-specific responses

1 Jan 2023

Abstract excerpt

Chronic liver injury leads to progressive liver fibrosis and ultimately cirrhosis, a major cause of morbidity and mortality worldwide. However, there are currently no effective anti-fibrotic therapies available, especially for late-stage patients, which is partly attributed to the major knowledge gap regarding liver cell heterogeneity and cell-specific responses in different fibrosis stages. To reveal the...

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PMID: 36994536
DOI: 10.24272/j.issn.2095-8137.2023.031

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