Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

MarR-Dependent Transcriptional Regulation of mmpSL5 Induces Ethionamide Resistance in Mycobacterium abscessus

29 Mar 2023

Abstract excerpt

Mycobacterium abscessus ( Mabs ) is an emerging nontuberculosis mycobacterial (NTM) pathogen responsible for a wide variety of respiratory and cutaneous infections that are difficult to treat with standard antibacterial therapy. Mabs has a high degree of both innate and acquired antibiotic resistance to most clinically relevant drugs, including standard anti-mycobacterial agents. Ethionamide (ETH), an inhibitor...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Mycobacterium research and diagnosis
Share to Quinazolinone synthesis and applications
Share to Tuberculosis Research and Epidemiology

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 36988462
DOI: 10.1128/aac.01350-22

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

MarR-Dependent Transcriptional Regulation of mmpSL5 Induces Ethionamide Resistance in Mycobacterium abscessusPMID 36988462Read ↗

MarR-Dependent Transcriptional Regulation of <i>mmpSL5</i> induces Ethionamide Resistance in <i>Mycobacterium abscessus</i>Semantic proximity Read ↗

Whole-Transcriptome and -Genome Analysis of Extensively Drug-Resistant Mycobacterium tuberculosis Clinical Isolates Identifies Downregulation of ethA as a Mechanism of Ethionamide Resistance.Semantic proximity Read ↗

MmpS5/MmpL5 as an efflux pump in Mycobacterium species.Semantic proximity Read ↗

The TetR Family Transcription Factor MAB_2299c Regulates the Expression of Two Distinct MmpS-MmpL Efflux Pumps Involved in Cross-Resistance to Clofazimine and Bedaquiline in Mycobacterium abscessusSemantic proximity Read ↗

Mycobacterial ethambutol responsive genes and implications in antibiotics resistance.Semantic proximity Read ↗

MmpL3 as a Target for the Treatment of Drug-Resistant Nontuberculous Mycobacterial InfectionsSemantic proximity Read ↗

Resistance to Thiacetazone Derivatives Active against Mycobacterium abscessus Involves Mutations in the MmpL5 Transcriptional Repressor MAB_4384.Semantic proximity Read ↗

Mycobacterial Membrane Protein Large 3 (MmpL3) Inhibitors: A Promising Approach to Combat TuberculosisSemantic proximity Read ↗

Dissecting erm (41)-Mediated Macrolide-Inducible Resistance in Mycobacterium abscessusSemantic proximity Read ↗

Mycobacterium abscessus HelR interacts with RNA Polymerase to confer intrinsic rifamycin resistanceSemantic proximity Read ↗

Comparative transcriptomic profiling of pyrazinamide resistance in Mycobacterium tuberculosis.Semantic proximity Read ↗

mbtD and celA1 association with ethambutol resistance in Mycobacterium tuberculosis: A multiomics analysisSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.