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SCN9A rs6746030 Polymorphism and Pain Perception in Combat Athletes and Non-Athletes.

Genes - 16 Mar 2023

Leźnicka Katarzyna, Pawlak Maciej, Sawczuk Marek, Gasiorowska Agata, Leońska-Duniec Agata

Abstract excerpt

One of the genes associated with pain perception is SCN9A, which encodes an α-subunit of the voltage gated sodium channel, NaV1.7, a crucial player in peripheral pain sensation. It has been suggested that a common missense polymorphism within SCN9A (rs6746030; G>A; R1150W) may affect nociception in the general population, but its effects of pain perception in athletes remain unknown. Therefore, the aim of the...

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PMID: 36981004
DOI: 10.3390/genes14030733
PMCID: PMC10048703

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