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Article

Single nucleotide variants in VDR and GC genes associated with osteoporosis in Mexican women.

Climacteric : the journal of the International Menopause Society - 1 Jun 2026

Sevilla-Montoya Rosalba, Flores-Quijano María Eugenia, Tolentino-Dolores Mari Cruz, Martínez-Meza Yuridia, Ortiz-Luna Guillermo Federico, Castañeda-de-la-Fuente Angélica, López-Rodriguez Larissa, Rodríguez-González Gerardo, León-Madero Luis Felipe, Borboa-Olivares Héctor, Velázquez-Cruz Rafael, Fernández-Hernández Liliana, Hidalgo-Bravo Alberto

Abstract excerpt

OBJECTIVE: Osteoporosis is a prevalent multifactorial disease. Single nucleotide variants (SNVs) have been studied as a potential tool for estimating disease risk. These findings suggest that the GG genotype of rs2282679 in the vitamin D-binding protein (GC) gene may confer a protective effect against osteoporosis in postmenopausal Mexican women, whereas no significant association was found for rs4516035 in the...

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Source

Identifiers

PMID: 41385400
DOI: 10.1080/13697137.2025.2584063

Genes

GC
VDR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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