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Mapping Immune Correlates and Surfaceome Genes in BRAF Mutated Colorectal Cancers

21 Feb 2023

Abstract excerpt

Despite the impressive results obtained with immunotherapy in several cancer types, a significant fraction of patients remains unresponsive to these treatments. In colorectal cancer (CRC), B-RafV600 mutations have been identified in 8-15% of the patients. In this work we interrogated a public dataset to explore the surfaceome of these tumors and found that several genes, such as GP2, CLDN18, AQP5, TM4SF4, NTSR1,...

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PMID: 36975409
DOI: 10.3390/curroncol30030196

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