Article
Clinical and Immunologic Characteristics of Colorectal Cancer Tumors Expressing LY6G6D.
International journal of molecular sciences - 14 May 2024
Sanvicente García Adrián, Pedregal Manuel, Paniagua-Herranz Lucía, Díaz-Tejeiro Cristina, Nieto-Jiménez Cristina, Pérez Segura Pedro, Munkácsy Gyöngyi, Győrffy Balázs, Calvo Emiliano, Moreno Víctor, Ocaña Alberto
Abstract excerpt
The identification of targets that are expressed on the cell membrane is a main goal in cancer research. The Lymphocyte Antigen 6 Family Member G6D (LY6G6D) gene codes for a protein that is mainly present on the surface of colorectal cancer (CRC) cells. Therapeutic strategies against this protein like the development of T cell engagers (TCE) are currently in the early clinical stage. In the present work, we...
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