Article
Chronic pain, depression and cardiovascular disease linked through a shared genetic predisposition: Analysis of a family-based cohort and twin study.
PloS one - 1 Jan 2017
van Hecke Oliver, Hocking Lynne J, Torrance Nicola, Campbell Archie, Padmanabhan Sandosh, Porteous David J, McIntosh Andrew M, Burri Andrea V, Tanaka Haruka, Williams Frances M K, Smith Blair H
Abstract excerpt
BACKGROUND: Depression and chronic pain are the two most important causes of disability (Global Burden of Disease Study 2013). They occur together more frequently than expected and both conditions have been shown to be co-morbid with cardiovascular disease. Although shared socio-demographic risk factors (e.g. gender, deprivation) might explain the co-morbidity of these three conditions, we hypothesised that these...
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