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Article

Mendelian randomization highlights sleep disturbances mediated the effect of depression on chronic pain.

Brain and behavior - 1 Jul 2024

Zhu Yingchao, Bi Yaodan, Zhu Tao

Abstract excerpt

INTRODUCTION: Depression and chronic pain are significant contributors to the global burden of disease. Previous research has revealed complex relationships between these two conditions, which may be influenced by sleep quality. However, observational studies have limitations, including confounding factors and reverse causation. This study aims to explore the mediating effects of sleep on the relationship between...

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Identifiers

PMID: 38967065
DOI: 10.1002/brb3.3596
PMCID: PMC11224770

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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