Article
Life course effects of genetic susceptibility to higher body size on body fat and lean mass: prospective cohort study.
International journal of epidemiology - 5 Oct 2023
Waterfield Scott, Richardson Tom G, Davey Smith George, O'Keeffe Linda M, Bell Joshua A
Abstract excerpt
BACKGROUND/OBJECTIVES: Different genetic variants are associated with larger body size in childhood vs adulthood. Whether and when these variants predominantly influence adiposity are unknown. We examined how genetic variants influence total body fat and total lean mass trajectories. METHODS: Data were from the Avon Longitudinal Study of Parents and Children birth cohort (N = 6926). Sex-specific genetic risk...
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