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Assisted oocyte activation does not overcome recurrent embryo developmental problems

17 Mar 2023

Abstract excerpt

STUDY QUESTION: Can recurrent embryo developmental problems after ICSI be overcome by assisted oocyte activation (AOA)? SUMMARY ANSWER: AOA did not improve blastocyst formation in our patient cohort with recurrent embryo developmental problems after ICSI. WHAT IS KNOWN ALREADY: The use of AOA to artificially induce calcium (Ca2+) rises by using Ca2+ ionophores (mainly calcimycin and ionomycin) has been reported...

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PMID: 36931261
DOI: 10.1093/humrep/dead051

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