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Article

Mitochondrial-nuclear coadaptation revealed through mtDNA replacements in Saccharomyces cerevisiae.

BMC evolutionary biology - 25 Sept 2020

Nguyen Tuc H M, Sondhi Sargunvir, Ziesel Andrew, Paliwal Swati, Fiumera Heather L

Abstract excerpt

BACKGROUND: Mitochondrial function requires numerous genetic interactions between mitochondrial- and nuclear- encoded genes. While selection for optimal mitonuclear interactions should result in coevolution between both genomes, evidence for mitonuclear coadaptation is challenging to document. Genetic models where mitonuclear interactions can be explored are needed. RESULTS: We systematically exchanged mtDNAs...

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Identifiers

PMID: 32977769
DOI: 10.1186/s12862-020-01685-6
PMCID: PMC7517635

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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