Article
Hybridization drives mitochondrial DNA degeneration and metabolic shift in a species with biparental mitochondrial inheritance.
Genome research - 1 Jan 2000
Hénault Mathieu, Marsit Souhir, Charron Guillaume, Landry Christian R
Abstract excerpt
Mitochondrial DNA (mtDNA) is a cytoplasmic genome that is essential for respiratory metabolism. Although uniparental mtDNA inheritance is most common in animals and plants, distinct mtDNA haplotypes can coexist in a state of heteroplasmy, either because of paternal leakage or de novo mutations. mtDNA integrity and the resolution of heteroplasmy have important implications, notably for mitochondrial genetic...
Topics
- Animals
- DNA, Mitochondrial
- Genes, Mitochondrial
- Mitochondria
- Hybridization, Genetic
- Genotype
- Saccharomyces cerevisiae