Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Functional characterization of archaic-specific variants in mitonuclear genes: insights from comparative analysis in S. cerevisiae.

Human molecular genetics - 21 Jun 2024

Aneli Serena, Ceccatelli Berti Camilla, Gilea Alexandru Ionut, Birolo Giovanni, Mutti Giacomo, Pavesi Angelo, Baruffini Enrico, Goffrini Paola, Capelli Cristian

Abstract excerpt

Neanderthal and Denisovan hybridisation with modern humans has generated a non-random genomic distribution of introgressed regions, the result of drift and selection dynamics. Cross-species genomic incompatibility and more efficient removal of slightly deleterious archaic variants have been proposed as selection-based processes involved in the post-hybridisation purge of archaic introgressed regions. Both...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alleles
Share to Genetic Introgression

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Genetic Variation

Share to Mitochondria

Share to Neanderthals

Share to Saccharomyces cerevisiae

Share to Saccharomyces cerevisiae Proteins

Source

Identifiers

PMID: 38558123
DOI: 10.1093/hmg/ddae057

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Functional characterization of archaic-specific variants in mitonuclear genes: insights from comparative analysis in S. cerevisiae.PMID 38558123Read ↗

Evolutionary Trajectories are Contingent on Mitonuclear Interactions.Semantic proximity Read ↗

Heterologous Inferential Analysis (HIA) and Other Emerging Concepts: In Understanding Mitochondrial Variation In Pathogenesis: There is no More Low-Hanging Fruit.Semantic proximity Read ↗

A catalog of neutral and deleterious polymorphism in yeast.Semantic proximity Read ↗

The genetics of the many forms of diversity.Semantic proximity Read ↗

From genotype to phenotype with 1,086 near telomere-to-telomere yeast genomes.Semantic proximity Read ↗

Mitonuclear interplay in yeast: from speciation to phenotypic adaptation.Semantic proximity Read ↗

Genome evolution across 1,011 Saccharomyces cerevisiae isolates.Semantic proximity Read ↗

Genome sequencing and comparative analysis of Saccharomyces cerevisiae strain YJM789.Semantic proximity Read ↗

The role of the mitochondrial ribosome in human disease: searching for mutations in 12S mitochondrial rRNA with high disruptive potential.Semantic proximity Read ↗

Exploring the impact of mitonuclear discordance on disease in Latin American admixed populationsSemantic proximity Read ↗

Mechanistic Modelling of Recessive Disease through Allelic Integration of Variant EffectsSemantic proximity Read ↗

Mitochondrial genetics revisited.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.