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Article

C2729T mutation associated with HBV mother-to-child transmission reduces HBV production via suppressing LHBs expression.

Virulence - 1 Dec 2023

Liu Minmin, Song Yarong, Li Yi, Yang Xingwen, Zhuang Hui, Li Jie, Wang Jie

Abstract excerpt

Mother-to-child transmission (MTCT) is still the main route of hepatitis B virus (HBV) infection. However, the virological factors affecting HBV MTCT have not been fully elucidated. In this study, based on a prospective cohort of mother-infant pairs with positive maternal hepatitis B surface antigen (HBsAg), we found that the average nucleotide mutation rate of HBV preS1 promoter (SPI) region in the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 36919573
DOI: 10.1080/21505594.2023.2189676
PMCID: PMC10026911

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

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