Article
Maternal A90V mutation in the PreS1 gene of sub-genotype C2 hepatitis B virus is associated with intrauterine transmission.
Revista do Instituto de Medicina Tropical de Sao Paulo - 1 Jan 2023
Yi Linzhu, Wu Jiaxin, Yang Zhiqing, Li Yandi, Lian Jia, Yao Tian, Feng Shuying, Wang Bo, Feng Yongliang, Wang Suping
Abstract excerpt
PreS/S gene mutations could impact virus secretion, infection and immune evasion. However, the relationship between PreS/S mutations and intrauterine transmission has not yet been clarified. Thus, we aimed to explore the associations between PreS/S gene mutations of HBV isolated from mothers and intrauterine transmission. We analyzed the mutations of PreS/S regions of the HBV genome in mothers with HBV DNA levels...
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