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Article

Lifetime cannabis use and childhood trauma associated with CNR1 genetic variants increase the risk of psychosis: findings from the STREAM study.

Revista brasileira de psiquiatria (Sao Paulo, Brazil : 1999) - 1 Jan 2000

Loureiro Camila Marcelino, Corsi-Zuelli Fabiana, Fachim Helene Aparecida, Shuhama Rosana, de Oliveira Adrielle Martins, Menezes Paulo Rossi, Dalton Caroline F, Louzada-Junior Paulo, Belangero Sintia Iole, Coeli-Lacchini Fernanda, Reynolds Gavin P, Lacchini Riccardo, Del-Ben Cristina Marta

Abstract excerpt

OBJECTIVES: Gene-environment interactions increase the risk of psychosis. The objective of this study was to investigate gene-gene and gene-environment interactions in psychosis, including single nucleotide variants (SNVs) of dopamine-2 receptor (D2R), N-methyl-d-aspartate receptor (NMDAR), and cannabinoid receptor type 1 (CB1R), lifetime cannabis use, and childhood trauma. METHODS: Twenty-three SNVs of genes...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Polymorphism, Single Nucleotide

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Share to Receptor, Cannabinoid, CB1

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Identifiers

PMID: 36918037
DOI: 10.47626/1516-4446-2022-2882
PMCID: PMC10288472

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