Article
Nongenetic Factors Associated With Psychotic Experiences Among UK Biobank Participants: Exposome-Wide Analysis and Mendelian Randomization Analysis.
JAMA psychiatry - 1 Sept 2022
Lin Bochao Danae, Pries Lotta-Katrin, Sarac Halil Suat, van Os Jim, Rutten Bart P F, Luykx Jurjen, Guloksuz Sinan
Abstract excerpt
Importance: Although hypothesis-driven research has identified several factors associated with psychosis, this one-exposure-to-one-outcome approach fails to embrace the multiplicity of exposures. Systematic approaches, similar to agnostic genome-wide analyses, are needed to identify genuine signals. Objective: To systematically investigate nongenetic correlates of psychotic experiences through data-driven...
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