Liquid crystalline matrix-induced viscoelastic mechanical stimulation modulates activation and phenotypes of macrophage.

Abstract excerpt

Accumulating evidence indicates that the mechanical microenvironment exerts profound influences on inflammation and immune modulation, which are likely to be key factors in successful tissue regeneration. The elastic modulus (Em) of the matrix may be a useful adjustable property to control macrophage activation and the overall inflammatory response. This study constituted a series of Em-tunable liquid crystalline...

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• Inflammation
• Macrophage Activation
• Macrophages
• Phenotype