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Article

A "sandwich" cell culture platform with NIR-responsive dynamic stiffness to modulate macrophage phenotypes.

Biomaterials science - 7 Apr 2021

Yuan Peiqi, Luo Yilun, Luo Yu, Ma Lie

Abstract excerpt

Considering the key roles of macrophages in tissue repair and immune therapy, designing smart biomaterials able to harness macrophage phenotypes on demand during the healing process has become a promising strategy. Here, a novel "sandwich" cell culture platform with near-infrared (NIR) responsive dynamic stiffness was fabricated to polarize bone marrow-derived macrophages (BMDMs) in situ for revealing the...

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PMID: 33576368
DOI: 10.1039/d0bm02194f

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