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Development and validation of an RNA sequencing panel for gene fusions in soft tissue sarcoma

3 Mar 2022

Abstract excerpt

Gene fusions are one of the most common genomic alterations in soft tissue sarcomas (STS), which contain more than 70 subtypes. In this study, a custom-designed RNA sequencing panel including 67 genes was developed and validated to identify gene fusions in STS. In total, 92 STS samples were analyzed using the RNA panel and 95.7% (88/92) successfully passed all the quality control parameters. Fusion transcripts...

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PMID: 35238118
DOI: 10.1111/cas.15317

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