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In search of an ideal template for therapeutic genome editing: A review of current developments for structure optimization

22 Feb 2023

Abstract excerpt

Gene therapy is a fast developing field of medicine with hundreds of ongoing early-stage clinical trials and numerous preclinical studies. Genome editing (GE) now is an increasingly important technology for achieving stable therapeutic effect in gene correction, with hematopoietic cells representing a key target cell population for developing novel treatments for a number of hereditary diseases, infections and...

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Identifiers

PMID: 36911237
DOI: 10.3389/fgeed.2023.1068637

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