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Machine learning for genetic prediction of chemotherapy toxicity in cervical cancer

10 Mar 2023

Abstract excerpt

BACKGROUND: Locally advanced cervical cancer (LACC) is frequently treated with neoadjuvant chemotherapy (NACT), which includes paclitaxel and platinum. However, the development of severe chemotherapy toxicity is a barrier to successful NACT. Phosphatidylinositol 3-kinase (PI3K)/serine/threonine kinase (AKT) pathway is related to the occurrence of chemotherapeutic toxicity. In this research work, we employ a...

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PMID: 36906972
DOI: 10.1016/j.biopha.2023.114518

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