Construction of possible integrated predictive index based on EGFR and ANXA3 polymorphisms for chemotherapy response in fluoropyrimidine-treated Japanese gastric cancer patients using a bioinformatic method.

doi:10.1186/s12885-015-1721-z

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Article

Construction of possible integrated predictive index based on EGFR and ANXA3 polymorphisms for chemotherapy response in fluoropyrimidine-treated Japanese gastric cancer patients using a bioinformatic method.

BMC cancer - 16 Oct 2015

Takahashi Hiro, Kaniwa Nahoko, Saito Yoshiro, Sai Kimie, Hamaguchi Tetsuya, Shirao Kuniaki, Shimada Yasuhiro, Matsumura Yasuhiro, Ohtsu Atsushi, Yoshino Takayuki, Doi Toshihiko, Takahashi Anna, Odaka Yoko, Okuyama Misuzu, Sawada Jun-Ichi, Sakamoto Hiromi, Yoshida Teruhiko

Abstract excerpt

BACKGROUND: Variability in drug response between individual patients is a serious concern in medicine. To identify single-nucleotide polymorphisms (SNPs) related to drug response variability, many genome-wide association studies have been conducted. METHODS: We previously applied a knowledge-based bioinformatic approach to a pharmacogenomics study in which 119 fluoropyrimidine-treated gastric cancer patients were...

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Identifiers

PMID: 26475168
DOI: 10.1186/s12885-015-1721-z
PMCID: PMC4609065

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EGFR
ANXA3

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

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