Article
Time-to-event modeling for achieving a stable warfarin dose using genetic and non-genetic covariates.
Advances in clinical and experimental medicine : official organ Wroclaw Medical University - 1 Mar 2023
Sridharan Kannan, Banna Rashed Abdulla Al, Husain Aisha
Abstract excerpt
BACKGROUND: Time-to-event modeling is gaining importance in drug dosage determination, particularly using pharmacometrics approaches. OBJECTIVES: To evaluate the various time-to-event models for estimating the time to achieve a stable warfarin dose in the Bahraini population. MATERIAL AND METHODS: A cross-sectional study evaluating the non-genetic and genetic covariates (single nucleotide polymorphisms (SNPs) in...
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