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Article

Oral anticoagulants: Pharmacogenetics Relationship between genetic and non-genetic factors.

Blood reviews - 1 May 2008

D'Andrea Giovanna, D'Ambrosio Rosa, Margaglione Maurizio

Abstract excerpt

Oral anticoagulants, the main drugs used for the prevention and treatment of thromboembolic diseases, exhibit a greater than 10-fold inter-individual variability in the dose requirement to achieve a therapeutic response. The relationship between the dose prescribed and the individual response is regulated by genetic and environmental factors. In particularly, molecular analysis of two genes, encoding for the...

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Source

Identifiers

PMID: 18234403
DOI: 10.1016/j.blre.2007.11.004

Genes

VKORC1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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