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Article

Missed opportunities: Germline testing following tumor sequencing.

Gynecologic oncology - 1 Aug 2025

Karpel Hannah C, Sasse Simone, Pothuri Bhavana

Abstract excerpt

PURPOSE: Tumor next generation sequencing (NGS) may identify potential germline DNA mutations associated with cancer susceptibility. We describe the frequency of tumor NGS results in patients meeting ESMO 2019 recommendations for germline genetic testing (GT) and reasons for not undergoing germline GT. METHODS: A retrospective study (Sept. 2019-Feb. 2022) in a large, urban healthcare system identified patients...

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Identifiers

PMID: 40554180
DOI: 10.1016/j.ygyno.2025.06.011

Genes

BRCA1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

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