Article
Review: Mammalian Target of Rapamycin (mTOR) Pathway Is Critical in Developing Most Renal Cell Tumors.
Annals of clinical and laboratory science - 1 Jan 2023
Zhang Kevin J, Qu Zhenhong, Pszenica Elan, Hafron Jason M, Zhang Ping L, Brown Robert E
Abstract excerpt
OBJECTIVE: Various renal cell carcinomas (RCC) are derived from different segments of the renal tubular origin, which determines their morphological and immunohistochemical phenotype and their molecular signaling pathway as a therapeutic target. Most of these tumors utilize the mammalian target of rapamycin (mTOR) pathway to activate pathways involving metabolic and nutritional supplies. METHODS: Overexpressed...
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