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Article

Phenotype versus genotype discordant rifampicin susceptibility testing in tuberculosis: implications for a diagnostic accuracy.

Microbiology spectrum - 11 Jan 2024

Qadir Mehmood, Faryal Rani, Khan Muhammad Tahir, Khan Sajjad Ahmed, Zhang Shulin, Li Weimin, Wei Dong Qing, Tahseen Sabira, McHugh Timothy D

Abstract excerpt

IMPORTANCE: An accurate diagnosis of drug resistance in clinical isolates is an important step for better treatment outcomes. The current study observed a higher discordance rate of rifampicin resistance on Mycobacteria Growth Indicator Tube (MGIT) drug susceptibility testing (DST) than Lowenstein-Jenson (LJ) DST when compared with the rpoB sequencing. We detected a few novel mutations and their combination in...

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Identifiers

PMID: 37982632
DOI: 10.1128/spectrum.01631-23
PMCID: PMC10783056

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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