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Article

E26 transformation-specific variant 4 as a tumor promotor in human cancers through specific molecular mechanisms

28 Jul 2021

Abstract excerpt

E26 transformation-specific (ETS) variant 4 (ETV4) is an important transcription factor that belongs to the ETS transcription factor family and is essential for much cellular physiology. Recent evidence has revealed that ETV4 is aberrantly expressed in many types of tumors, and its overexpression is related to poor prognosis of cancer patients. Additionally, increasing studies have identified that ETV4 promotes...

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PMID: 34553037
DOI: 10.1016/j.omto.2021.07.012

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