Article
Association of laxatives use with incident dementia and modifying effect of genetic susceptibility: a population-based cohort study with propensity score matching.
BMC geriatrics - 4 Mar 2023
Feng Jiangtao, Zheng Nan, Fan Xutong, Li Shu, Jiang Yuhan, Yi Xianfu, Yang Hongxi
Abstract excerpt
BACKGROUND: Constipation was associated with incidence of dementia and cognitive decline. Laxatives are the mainstay of constipation management and are commonly used among older populations for both treatment and prevention of constipation. However, the association between use of laxatives and incident dementia, and whether laxatives use may modify the effect of genetic predisposition on dementia remains unclear....
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