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Article

Neuropsychiatric Disorders and Constipation: Unraveling Causal Links Through Genetic Analysis.

Brain and behavior - 1 Mar 2026

Zhao Guojie, Ren Haixia, Zhang Yi, Wang Zhi, Yang Qiao, Liu Shuang, Li Minzhen, Xiang Zhiyu, Liu Jingwen

Abstract excerpt

BACKGROUND: Numerous observational studies have suggested a relationship between neuropsychiatric disorders and constipation. However, the specific causal relationships remain unclear. Mendelian randomization (MR) serves as a proven strategy for examining the causal relationships between genetic exposures and outcomes. In the present study, we used a two-sample Mendelian randomization (TSMR) analysis to...

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Identifiers

PMID: 41782465
DOI: 10.1002/brb3.71302
PMCID: PMC12961347

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

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